Location: Houston, TX
Cap-Exempt H-1B Position — No lottery required
The Research Internship position provides hands-on experience in translational cancer research, with a focus on prostate cancer bone metastasis (bmPCa). The intern will contribute to cutting-edge studies centered on liquid biopsies and extracellular vesicles (EVs), including their isolation, molecular characterization, and functional evaluation in preclinical models and clinical samples. This role offers exposure to advanced transcriptomic and proteomic techniques, as well as in vivo modeling, within a collaborative and highly innovative research environment. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. **LEARNING OBJECTIVES** 1. Culturing tumor cell lines and handling patient-derived xenograft (PDX) samples 2. Isolating extracellular vesicles using a variety of established methods 3. Performing RNA and protein extraction for downstream molecular profiling (RNA-seq, proteomics) 4. Conducting in vivo experiments, including small animal handling, treatment, and monitoring 5. Operating specialized instrumentation (e.g., flow cytometry, Nanosight, IVIS, MRI) for EV analysis and tumor growth measurements. 6. Supporting data analysis and visualization using tools such as ImageJ and/or MATLAB 7. Maintaining accurate experimental records and contributing to data interpretation 8. Collaborating effectively with team members and communicating findings clearly 9. Computer literacy: - Needs to be capable of generating electronic versions of data and images for analysis and presentation. Experience in cloud-based image and data management is preferred. 10. Laboratory Inventory management: - Must be able to manage inventories and order material for the laboratory in a timely fashion. Must work with department members and collaborators to ensure the consistent flow of information and quality control. MARGINAL FUNCTIONS: Conduct Library Work: - Reads and understan