Location: Irvine, CA
Cap-Exempt H-1B Position — No lottery required
Overview: Founded in 1965, **UC Irvine** is a member of the prestigious Association of American Universities and is ranked among the nation’s top 10 public universities by U.S. News & World Report. The campus has produced five Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UC Irvine has more than 36,000 students and offers 224 degree programs. It’s located in one of the world’s safest and most economically vibrant communities and is Orange County’s second-largest employer, contributing $7 billion annually to the local economy and $8 billion statewide. To learn more about UC Irvine, visit www.uci.edu. In the La Spada laboratory, we apply the tools of molecular genetics, neuroscience, and functional genomics to understand the mechanisms of neurodegenerative disease. The repertoire of diseases being actively investigated in the lab include Spinal and Bulbar Muscular Atrophy, Spinocerebellar Ataxia Types 2 and 7, Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease Responsibilities: Part-time (20 hrs/wk) research intern is needed to assist on research projects at a UCI lab (La Spada, located in ISEB). This is not a work-study position. The intern will have a 1000 working hours maximum. The candidate must be able to work with flexibility depending on the animal experiments and occasional weekend work. The overall goal of the project is to investigate the role of microRNAs in spinocerebellar ataxia type 7 (SCA7) using novel mouse models and to evaluate therapeutic potential for neurodegenerative disease. Duties include rodent handling, perfusions, dissections, tissue cryosectioning, RNA extraction and analysis, molecular biology (protein and/or RNA analysis), immunofluorescence staining, microscopy, computational image analysis (ImageJ, NIS-Elements), and data analysis/presentation. Qualifications: **Required:** - Mouse handling - Mo