Location: Boston, MA
Cap-Exempt H-1B Position — No lottery required
Job Ref: JR-4346 Location: 450 Brookline Ave, BOSTON, MA 02215 Category: Research Laboratory Employment Type: Full time Work Location: Hybrid: 2-3 days onsite/week Salary/Pay Rate: $85,000.00 - $104,650.00 per year **Overview** The Center for Immune Oncology (CIO) at the Dana Farber Cancer Institute (DFCI) seeks a highly motivated Scientist II to support advanced analytics and data integration efforts across imaging, spatial proteomics, and high-dimensional cytometry data. The successful candidate will play a key role within the team in processing, analyzing, and modeling complex biomedical data — integrating spatial imaging, CyTOF, and clinical data — to enable discovery and translational research collaborations within the CIO. Environment and Opportunities The position offers opportunities to collaborate across a diverse set of projects within the Center for Immuno-Oncology (CIO), working closely with experts in computational biology, immunology, and clinical research. The Scientist II will sit within the Department of Data Science (DS) and be mentored by faculty directors from both CIO and DS. They will contribute within a small team to data-driven discovery, developing robust and scalable analytic tools for translational research. Key Duties and Responsibilities - Perform imaging and image analysis for spatial proteomics and multiplexed imaging datasets. - Conduct CyTOF and FCS data analysis, including data preprocessing, normalization, clustering, and visualization. - Analyze medical record data, integrating structured and unstructured clinical information as appropriate. - Manage and wrangle large, multimodal datasets, including high-resolution images and patient-level data. - Support database integration, including interoperability and linkage with REDCap and other institutional data systems. - Provide analytic and statistical support for CIO projects — emphasizing development of custom models, analytical pipelines, and reproducible outputs for collaborative