Location: Houston, TX
Cap-Exempt H-1B Position — No lottery required
## **Summary** The laboratory of Dr. Leo Luznik at Baylor College of Medicine is seeking a highly motivated and detail-oriented Research Technician II to join our translational research team. Our lab investigates the immune microenvironment in leukemia, with a focus on post-transplant immune reconstitution, T cell exhaustion, immune escape mechanisms, and novel immunotherapeutic strategies. We employ a range of cutting-edge techniques including single-cell multi-omics, in vivo leukemia models, and immunophenotyping platforms such as flow cytometry, CyTOF, and CITE-seq. ## **Job Duties** - Manages and maintains transgenic and immunocompromised mouse colonies, including genotyping, breeding, and induction protocols. - Conducts bone marrow transplantation, T cell isolation, adoptive cell transfer, and in vivo drug treatments. - Performs immune profiling using multicolor flow cytometry and assists in CyTOF and CITE-seq experiments. - Prepares biological samples (blood, marrow, spleen, lymph nodes) for downstream molecular assays including RNA/DNA extraction, qPCR, and single-cell library prep. - Assists with viral vector preparation and transduction protocols for immune and leukemia cell engineering. - Maintains accurate laboratory records, organizes inventory, and supports regulatory compliance (IACUC, biosafety). - Compiles experimental data and contributes to figures, lab reports, and scientific presentations. - Coordinates with internal core facilities for sequencing, histopathology, and cytometry services. - Assists in training students and new lab members as needed. - Supports experiments outside of regular hours, including weekends. - Performs other job-related duties as assigned. ## **Minimum Qualifications** - Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement. - Experience Required: None Required. ## **Preferred Qualifications** - Master's degree in basic science or a related field. - A