Location: Seattle, WA
Cap-Exempt H-1B Position — No lottery required
***Scientist III, Brain Tissue Cryopreservation and Functional Recovery – Brain Health*** The **mission** of the **Allen** **Institute** is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the **Allen Institute** focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science. The **Allen Institute** is launching a new accelerator on human brain health and disease. This initiative aims to dramatically accelerate our understanding of human brain structure and function, identify the molecular, cellular and circuit basis of disease progression, and pioneer new therapeutic strategies targeting vulnerable and affected cell types. Our mission focuses on taking a human-centric approach to understanding and treating disease, combining a large-scale open science discovery approach across multiple diseases, AI-based disease modeling, and translational programs in specific diseases to move from discovery to clinical application. We aim to make transformational change in understanding and treating brain disorders, the biggest health challenge of our time. Recent work by the Allen Institute has identified selective vulnerability of specific brain cell types in brain disease progression. In parallel, we are building on a decade of progress in pioneering human postmortem and neurosurgical brain tissue platforms and capabilities for assaying cell and circuit mechanisms of CNS diseases, with the goal to expand these platforms from brain atlasing into detailed functional studies with cell type targeted interventions. We are searching for an exceptional Scientist III to join an innovative project aiming to pioneer new approaches for human brain tissue preservation, including cryopreservation techniques compatible with full recovery of functional properties. The Scientist III hire will contri