Location: Houston, TX
Cap-Exempt H-1B Position — No lottery required
## **Summary** A newly funded postdoctoral position is available in Dr. Luznik's lab in the Department of Medicine at Baylor College of Medicine for highly motivated individuals interested in immunotherapy of hematologic malignancies. Central to this laboratory’s mission is an in-depth exploration of the basic mechanisms of immune response with a focus on direct clinical application. The long-term goal for the Postdoctoral Associate position is to generate several high-impact manuscripts and competitively apply for extramural funding toward an independent research career. The position can be tailored for physician-scientists with an interest in immunotherapy of leukemias. All the research work is published in leading journals, and the lab is a part of a large and vibrant cancer immunology and immunotherapy research community at Baylor College of Medicine. Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates. ## **Job Duties** - Designs and executes advanced immunological research experiments focused on understanding T-cell dysfunction and immune evasion mechanisms in hematologic malignancies, using both human samples and animal models. - Applies high-dimensional data analysis techniques, including single-cell RNA sequencing (scRNA-seq), multicolor flow cytometry, and systems biology approaches, to uncover novel immune cell states and therapeutic targets. - Develops and optimizes experimental protocols for cellular immunology, including trajectory inference and dimensionality reduction methods such as tSNE and UMAP, tailored to translational immunotherapy applications. - Analyzes and interprets complex datasets using bioinformatics tools (e.g., Seurat, Scanpy) and programming languages such as R or Python, contributing to mechanistic insights and clinical relevance. - Establishes and refines research protocols that integrate molecular biology and computational pipelines to support reproducibility an