Location: Rochester, MN
Cap-Exempt H-1B Position — No lottery required
CityRochester StateMN RemoteYES DepartmentInformation Technology **Why Mayo Clinic** Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. **Benefits Highlights** - Medical: Multiple plan options. - Dental: Delta Dental or reimbursement account for flexible coverage. - Vision: Affordable plan with national network. - Pre-Tax Savings: HSA and FSAs for eligible expenses. - Retirement: Competitive retirement package to secure your future. **Responsibilities** Mayo Clinic Genomics and Emerging Systems Unit is seeking a Software Engineer to design, develop, and maintain robust .NET-based back-end services supporting a broad portfolio of genomics and clinical applications. These systems operate across on-premises environments and modern cloud platforms, including Azure and Google Cloud Platform (GCP), and integrate with distributed services through secure APIs and web services. The Software Engineer will build and optimize services that handle complex genomic workflows, large-scale clinical datasets, and high-throughput data processing. This includes ensuring that all services meet strict performance, reliability, and accuracy requirements, scale effectively as data volumes grow, and remain resilient within hybrid cloud ecosystems. The role collaborates closely with Product Owners, Product Managers, Architects, and cross-functional engineering partners to translate requirements into well-architected, maintainable code. Responsibilities include designing and implementing services aligned to enterprise architecture, including cloud-ready APIs, data integrati