Location: Philadelphia, PA
Cap-Exempt H-1B Position — No lottery required
The Wistar Institute has an opening for a Computational Biology Post-Doctoral Fellow to join the laboratory of Dr. Avi Srivastava. The Srivastava Lab is a hybrid computational-experimental group that develops and applies cutting-edge single-cell genomics technologies to address fundamental questions in RNA biology and cancer. Our work spans the full arc from novel method development, including microfluidics-free single-cell long-read RNA sequencing platforms, to biological discovery using multi-omics approaches at single-cell resolution. We are seeking a highly motivated computational biologist with meaningful wet-lab experience (or a wet-lab scientist with strong computational skills) who is excited to work at this interface. The ideal candidate will contribute to projects involving the development of single-cell long-read sequencing methods, isoform-level transcriptomics, and multi-omics data integration in disease-relevant contexts. **The lab offers mentored training in:** - Single-cell and bulk multi-omics analysis - Long-read sequencing technologies and computational workflows (Oxford Nanopore, PacBio) - Novel library preparation and microfluidics-free single-cell platform development - High-performance algorithm design and software engineering for genomics - Cancer and RNA biology applications of single-cell technologies Candidates with a Ph.D. (or equivalent) in computational biology, genomics, molecular biology, or a related field are encouraged to apply. Hands-on experience with both computational analysis (e.g., single-cell RNA-seq pipelines, Python/R, Linux environments) and experimental molecular biology techniques is strongly preferred. At least one first-author peer-reviewed publication is required. In addition to applying online, interested applicants should e-mail their CV with publication list (published and in preparation), a cover letter detailing their research experience and interest in the lab, and three references to Dr. Avi Srivastava at asri